Aripiprazole treatment for coprophagia in autistic disorder.

Efficacy and Safety of Aripiprazole for Treatment of Irritability in Children with Autistic Disorder: An Open-Label Study

Emerging role of aripiprazole for treatment of irritability associated with autistic disorder in children and adolescents

Autistic disorder is a largely misunderstood and difficult to treat neurodevelopmental disorder. Three core domains of functioning are affected by autistic disorder, ie, socialization, communication, and behavior. Signs of autistic disorder may be present early, but are frequently overlooked, resulting in a delay in its diagnosis and a subsequent delay in treatment. No one definitive therapy is...

Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder.

OBJECTIVE The objective of this study was to evaluate short-term efficacy and safety of aripiprazole in the treatment of irritability in children and adolescents with autistic disorder who were manifesting behaviors such as tantrums, aggression, self-injurious behavior, or a combination of these. METHODS This 8-week, double-blind, randomized, placebo-controlled, parallel-group study was condu...

Aripiprazole: A Review of its Use in the Treatment of Irritability Associated with Autistic Disorder Patients Aged 6–17

A systematic review and meta-analysis were performed examining the efficacy of aripiprazole for the treatment of irritability associated with autistic disorder in children and adolescents. Aripiprazole was found to be more effective in reducing irritability compared with placebo at 8 weeks, SMD -0.64 [-0.90 to -0.39, P < 0.00001] as determined by the Aberrant Behaviour Checklist irritability su...

Aripiprazole improves social interaction in Taiwanese children with pervasive developmental disorder.

Aripiprazole, an atypical antipsychotic, is effective in children with psychosis and few adverse effects have been reported. However, little is known about the efficacy and safety of aripiprazole in the treatment of autistic or other pervasive developmental disorders. We report three children with pervasive developmental disorders who were treated with aripiprazole for associated behavioral syn...